Creatinine is a chemical waste molecule that is generated by muscles. Creatinine is produced from creatine, that produces energy for muscles. Approximately 2% of body’s creatine is converted to Creatinine every day. Creatinine is transported via the blood to the kidney, that filters it and dispose it through urine. For healthy people, the level is generally the same as the muscles growth in the body is relatively slow.
The kidney maintains the level of creatinine in the normal range. It is one of the indicators for Kidney Function. A high level of creatinine possibly indicates damage or malfunction of the kidney or possible kidney failure.
With Kidney Transplant patients, Creatinine is one the importantant levels that needs to be checked regularly and maintain within the normal Levels.
The Normal Levels are calculated, depending where you are. In Americas the it is calculated as mg/dl and in Europe as umol/L) The normal levels for Males are 60-110 umol/L and for females is about (45-90). This also varies for certain males or females where they are excessive muscular or extremely week. With older people the levels are a bit low. But on an average it is in the ranges specified.
If you are above this range that means that there is something wrong with the filtration of creatinine by your kidney and you could possibly be looking at a Kidney malfunction. This could also mean kidney failure.
With a blood test, the level of creatinine level can be determined and if things are not right, you doctor or consultant may contact you.
Creatinine plays an important part in your life when on Dialysis and especially importnat after a Kidney transplant. It is like the lifeline of the patient. After transplant, it is like an indicator that how well your kidney is working. Again, the levels could vary from one individual to another. But generally the more controlled it is, the better funciton of your transplanted kidney is.
I have personally have been having creatinine levels jumping up and down. Which is relatively common after a kidney transplant. But not with everyone. Some people are lucky and the kidney is well controlled and maintain by the body and everything is hunky dory. After my transplant my creatinine level was 800. Which is obviously very very high. Having such a major operation I was not much in my senses, but knew were not in order and they had to come in control with the right treatment. With luck i had the best doctors around in the hospital taking care. I was treated in Hammersmith Hospital, London.
I underwent a treatment of IVIG and plasma exchange. Both treatments acted like a miracle for me. I could see the graph falling down from 800 to 200 with 2 sessions of plasma exchange.(Each session consists of 5 exchanges. There is normally a gap of a day within these 5 exchnages). the results are monitored daily or perhaps more often and hence further treatment(s) can be decided. After complete 2 sessions, I personally felt better as kidney function was increasing and i started passing more uring (around 5 centilitres, as compared to 500 ml a day).
What can be done to lower Creatinine Level, after Transplant?
Personally, I researched a lot and talked to a lot of people. I got advise that I should drink more water, so kidney clears all the toxins, someone said that try detox teas, or detox treatments. But I guess, i could not find any answers or suggestion said with confidence or proven. Hence, i presume, that IViG treatment is the solution.
I have been admitted to Hospital many times after my transplant, as my creatinine levels have been high, and IViG has solved the problem. I am still hunting for some natural soltuion (Of course, we have treatments from the Hospital) but something which what I can do keep a balance and control of my kidney and it’s levels.
What are the reasons for elevated blood creatinine?
Any condition that impairs the function of the kidneys will probably raise the creatinine level in the blood. It is important to recognize whether the process leading to kidney dysfunction (kidney failure, azotemia) is longstanding or recent.
The most common causes of longstanding kidney disease in adults are high blood pressure and diabetes mellitus. Certain drugs can sometimes cause abnormally elevated creatinine levels. Serum creatinine can also transiently rise after ingestion of large amount of dietary meat.
Are there any symptoms associated with elevated blood creatinine levels?
The symptoms of kidney dysfunction (renal insufficiency) vary widely. Some people may have a incidental finding of severe kidney disease and elevated creatinine on routine blood work without having any symptoms at all. In others, depending on the cause of problem, many different symptoms may be present including:
Feeling dehydrated, fatigue, shortness of breath, confusion, or many other nonspecific symptoms.
I hope this information is good enough for the starters. Well, it is all by experience and Research. More to come.
A few questions in the end have been referrred from
And I would like to give them credit on this. thanks. And Good Luck.
Filed under: Blood, Kidney, Kidney Dialysis, Kidney Failure, Kidney Pre Transplant, Kidney Transplant, Plasma Exchange, Post Care - Transplant Tagged: | Blood tests, Creatinine, Kidney, Kidney Transplant, muscles, Plasma Exchange, Protein